Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: a randomized trial (DOI: 10.6133/apjcn.202003_29(1).0009) – 2020

Study information

Study title	Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: a randomized tria
Publication year	2020
Authors	Jianqin Sun, Huijing Bai, Jianxia Ma, Ruiyu Zhang, Hua Xie, Yanmei Zhang, Mingquan Guo, Jianfeng Yao
DOI	10.6133/apjcn.202003_29(1).0009
PubMed ID	N/A
Study design	Randomized controlled trial
Number of participants	104
Population	Chinese adults diagnosed with chronic functional constipation according to the Rome IV criteria.
Intervention	Flaxseed supplementation (50 g/day).
Comparator	Lactulose
Duration	4 weeks
Health claim	Flaxseed supplementation improves symptoms of chronic functional constipation and quality of life.
Outcome measured	Stool frequency, stool consistency, constipation symptom score, symptom remission, and quality of life.
Main result	Flaxseed significantly improved bowel movement frequency, stool consistency, constipation symptoms, and quality of life. Its efficacy was comparable or superior to lactulose for several outcomes, with good tolerability.
Risk of bias	Moderate. Randomized trial with an active comparator, but no clear description of allocation concealment or blinding, relatively small sample size, and short follow-up (4 weeks).
Funding	Supported by the Shanghai Municipal Health and Family Planning Commission (reported in the article).
Citation	Sun J, Bai H, Ma J, Zhang R, Xie H, Zhang Y, Guo M, Yao J. Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: a randomized trial. Asia Pac J Clin Nutr. 2020;29(1):61-67. doi:10.6133/apjcn.202003_29(1).0009.

Study title

Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: a randomized tria

Publication year

2020

Authors

Jianqin Sun, Huijing Bai, Jianxia Ma, Ruiyu Zhang, Hua Xie, Yanmei Zhang, Mingquan Guo, Jianfeng Yao

DOI

10.6133/apjcn.202003_29(1).0009

PubMed ID

N/A

Study design

Randomized controlled trial

Number of participants

104

Population

Chinese adults diagnosed with chronic functional constipation according to the Rome IV criteria.

Intervention

Flaxseed supplementation (50 g/day).

Comparator

Lactulose

Duration

4 weeks

Health claim

Flaxseed supplementation improves symptoms of chronic functional constipation and quality of life.

Outcome measured

Stool frequency, stool consistency, constipation symptom score, symptom remission, and quality of life.

Main result

Flaxseed significantly improved bowel movement frequency, stool consistency, constipation symptoms, and quality of life. Its efficacy was comparable or superior to lactulose for several outcomes, with good tolerability.

Risk of bias

Moderate. Randomized trial with an active comparator, but no clear description of allocation concealment or blinding, relatively small sample size, and short follow-up (4 weeks).

Funding

Supported by the Shanghai Municipal Health and Family Planning Commission (reported in the article).

Citation

Sun J, Bai H, Ma J, Zhang R, Xie H, Zhang Y, Guo M, Yao J. Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: a randomized trial. Asia Pac J Clin Nutr. 2020;29(1):61-67. doi:10.6133/apjcn.202003_29(1).0009.

Study information

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