| Study title | Effect of flaxseed or psyllium vs. placebo on management of constipation, weight, glycemia, and lipids: A randomized trial in constipated patients with type 2 diabetes |
|---|---|
| Publication year | 2019 |
| Authors | Niloofar Soltanian, Mohammad Janghorbani |
| DOI | 10.1016/j.clnesp.2018.11.002 |
| PubMed ID | 30661699 |
| Study design |
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| Number of participants | 77 |
| Population | Adults with type 2 diabetes suffering from constipation |
| Intervention | Dietary supplementation with flaxseed or psyllium |
| Comparator | Placebo/control group |
| Duration | 12 weeks |
| Health claim | Flaxseed and psyllium may improve constipation symptoms and metabolic parameters in patients with type 2 diabetes. |
| Outcome measured | Constipation symptoms, bowel function, body weight, glycemic parameters, lipid profile. |
| Main result | Flaxseed supplementation improved constipation management and showed beneficial effects on metabolic outcomes, including glycemic control and lipid parameters. Psyllium also improved constipation-related outcomes. |
| Risk of bias | Moderate risk of bias — randomized design is a strength; limitations include relatively small sample size and potential difficulty maintaining dietary intervention blinding. |
| Funding | Not clearly reported in available indexing information. |
| Citation | Soltanian N, Janghorbani M. Effect of flaxseed or psyllium vs. placebo on management of constipation, weight, glycemia, and lipids: A randomized trial in constipated patients with type 2 diabetes. Clin Nutr ESPEN. 2019;29:41-48. doi:10.1016/j.clnesp.2018.11.002. |